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The Top 10 Best-Selling Cannabis Strains in Missouri (2025 Edition)
by MHW | October 27, 2025

Gorilla Pie is a hybrid strain with balanced effects providing relaxation without overwhelming sedation, with a sweet and fruity flavor of berry and earth. It is effective for stress relief, pain management, and mood enhancement. MHW offers this strain, making it accessible to customers looking for a versatile option. THC: ~25–29% Illicit’s Gorilla Pie has topped the charts — and for good reason. It delivers heavy-hitting body effects while keeping the mind calm and stress-free. A favorite for both recreational use and for medical patients managing pain or insomnia. Animal Star Cookies is a balanced hybrid (50% indica/50% sativa) created by crossing Animal Cookies and Stardawg. It offers a stimulating and uplifting high, suitable for both day and night use, with effects including relaxation, creativity, and arousal. The flavor profile features sour apples, sweet red fruits, zesty citrus, and savory earthiness, with a skunky and apple aroma accented by diesel and earth. Medical benefits include relief from anxiety, depression, and pain, making it ideal for experienced consumers. Blending Animal Cookies and Star Dawg, this strain is deeply relaxing with a sweet-baked-good aroma that draws you in. Perfect for evenings or winding down after a long day. Hibernate, also known as Hibermate, is a potent indica strain with a heavy body high that promotes deep relaxation and sleep. Its genetics are not widely publicized, but it is effective for insomnia, pain, and anxiety. With a classic earthy and pungent flavor, it is a go-to strain at MHW for those needing tranquility, especially in the evening. THC: ~22–25% This true indica is designed for rest. It’s a great nighttime strain for those struggling with insomnia, muscle tension, or anxiety. “Hibernate” isn’t just a name — it’s a promise. THC: ~20–23% A Missouri-grown strain with purpose, Wounded Warrior Breath by Buoyant Bob’s is deeply calming with a sense of grounding. It's an ideal option for veterans and patients seeking emotional and physical relief. THC: ~22% This new favorite mixes tart lemon zest with subtle diesel for a refreshing and mentally engaging experience. Dawg Lemons is ideal for those needing a little daytime lift or creative push. Bruce Banner, a sativa-dominant hybrid from OG Kush and Strawberry Diesel, delivers a strong cerebral high with a relaxing body buzz. Its sweet and earthy flavor makes it perfect for managing stress, depression, and pain, with effects boosting mood and energy. Available at MHW, it is popular among customers seeking a balanced experience. THC: ~25–28% Named after the Hulk’s alter ego, Bruce Banner hits fast and strong — but with a clean, energetic high. It’s the ideal hybrid for getting things done while staying elevated. THC: ~24% Ghost OG blends a heavy body high with a soothing headspace. It's excellent for stress and nighttime use without being too heavy on the sedation. GMO Cookies, also known as Garlic Cookies, is an indica-dominant hybrid from Chemdawg and Girl Scout Cookies, with a unique flavor of garlic, mushroom, onion, and sweetness. Its deeply relaxing effects, often leading to couch-lock, are suitable for evening use, helping with pain relief, insomnia, and appetite stimulation. MHW carries this strain by ILLICIT, ensuring high quality for patients. Known for its funky aroma and full-body melt, GMO Cookies is not for the faint of heart. Ideal for seasoned consumers and patients with chronic pain. THC: ~20–23% A cross between White Widow and Cinderella 99, White 99 offers an upbeat high that doesn’t compromise mental clarity. It’s perfect for daytime use or social settings. THC: ~21–24% CAPS Frozen Lemons is a vibrant, citrus-forward sativa flower known for delivering a focused, energizing high without overwhelming the senses. It's ideal for daytime use, creative work, or mood elevation — and the bright, zesty terpene profile makes it a favorite for flavor chasers. While the top 10 strains dominate sales charts, several other noteworthy options are rising in popularity at Missouri Health & Wellness dispensaries. Whether you’re an edibles fan or a flower purist, these honorable mentions deserve your attention: Sour Tsunami, a sativa-dominant hybrid from Sour Diesel and NYC Diesel, is known for its high CBD content, offering balanced effects that relieve pain and anxiety without heavy sedation. Its diesel-like flavor with citrus hints makes it ideal for therapeutic use with minimal psychoactive effects. At MHW, it is available for patients seeking medical benefits. THC: ~15–18% This unique strain is known for having higher CBD content alongside modest THC levels, offering relief without intense psychoactive effects. Ideal for daytime pain management or anxiety reduction. Violet Fog is an indica-dominant hybrid (80% indica/20% sativa) from Grape Gasoline and Khalifa Mints, known for its relaxing, sleepy, and euphoric effects, perfect for evening use. Its aroma includes sweet rotting grapes and old-school skunkiness, with a taste of sweet, fruity grape and spicy, skunky notes. It helps alleviate stress, insomnia, and chronic pain, making it a favorite for indica enthusiasts. Known for its mysterious name and powerful effects, Violet Fog delivers a strong, tranquilizing high that lingers. It's great for patients managing insomnia, migraines, or high stress. THC: ~20–22% A relaxing strain with legendary genetics. It’s a consistent pick for those seeking pain relief or a good night’s sleep — plus, the Flora Farms brand has deep roots in Missouri. These hybrid gummies are not only delicious but designed for experienced users who need potent, long-lasting effects. The "Gold" series from Ostara has developed a loyal following among medical users looking for strong relief. Whether you’re looking for the gassy punch of GMO Cookies or the citrus burst of Clementine, access to top-tier cannabis products is key — and Missouri Health & Wellness Dispensaries makes it easy. With several locations across the state, you can explore many of these best-selling strains in person or online. Each location has its own curated menu with rotating strains from local cultivators like Illicit, Flora Farms, SolHaus, and more. You can browse menus online, check stock in real-time, and even place orders for pickup. 💡 Pro tip: Their staff is well-versed in each strain’s effects, helping patients and adult-use consumers alike find the right product for their goals. Choosing the Right Strain for You For pain or insomnia: Go for heavy Indicas like Hibernate, Bubba Fett, or GMO Cookies. For mood and energy: Try uplifting Sativas like Clementine or Lemon Haze. For balance and creativity: Reach for hybrids like Bruce Banner or Gorilla Pie. For a mellow intro: Sour Tsunami or lower-THC options are a gentle starting point. At Missouri Health & Wellness, expert budtenders can guide you through strain selections and help match you with the product that best fits your needs — whether you’re a medical patient or a recreational shopper.1. Illicit Gorilla Pie (Hybrid)
Dominant Effects: Relaxation, euphoria, body-melt
Flavor: Fruity gas with creamy notesWhy It’s Popular:
2. Illicit Animal Star Cookies (Hybrid)
THC: ~26%
Effects: Euphoric, stoney, mentally calming
Flavor: Sweet, earthy, cookie doughWhy It’s Popular:
3. Illicit Hibernate (Indica)
Effects: Sedating, calming, couch-lock
Flavor: Skunky pine with herbal notesWhy It’s Popular:
4. Buoyant Bob's Wounded Warrior Breath (Indica-Hybrid)
Effects: Relaxing, introspective, physically calming
Flavor: Earthy with hints of mint and gasWhy It’s Popular:
Missouri Grown: This locally celebrated strain is available at Missouri Health & Wellness locations and praised by both medical users and everyday consumers.5. Illicit Dawg Lemons (Sativa-Hybrid)
Effects: Focused, mood-lifting, light energy
Flavors: Citrus and gasWhy It’s Popular:
6. Illicit Bruce Banner (Sativa-Hybrid)
Effects: Euphoric, cerebral, clear-headed
Flavor: Diesel with a sweet berry twistWhy It’s Popular:
7. Illicit Ghost OG (Hybrid)
Effects: Relaxed, mentally calm, slightly sedating
Flavor: Earthy, citrus, pineWhy It’s Popular:
8. Illicit GMO Cookies (Indica-Hybrid)
THC: ~25%
Effects: Heavily relaxing, stress-reducing, mind-numbing
Flavor: Garlic, mushroom, and gasWhy It’s Popular:
9. Flora Farms White 99 (Sativa)
Effects: Happy, focused, giggly
Flavor: Citrus and sweetnessWhy It’s Popular:
10. Vivid CAPS Frozen Lemons (Sativa)
Effects: Uplifting, clear-headed, energetic
Flavor: Tart lemon, citrus zest, slight dieselWhy It’s Popular:
Honorable Mentions: Other Popular Picks at Missouri Health & Wellness
Illicit Sour Tsunami (Sativa-Hybrid)
Effects: Balanced, calming, slight upliftWhy It’s Gaining Attention:
Illicit Violet Fog (Indica)
THC: ~23%
Effects: Heady, sleepy, euphoricWhy It’s Gaining Attention:
Flora Farms Bubba Fett (Indica)
Effects: Heavy body high, relaxing, stoneyWhy It’s Gaining Attention:
Edibles Spotlight: Ostara Gold Super High-Dose Gummies
THC: 100mg per pack
Why They’re Popular:
Where to Find These Strains in Missouri
Missouri Health & Wellness Dispensary Locations Include:
Final Thoughts:
There’s no one-size-fits-all when it comes to cannabis. The best strain for someone dealing with chronic pain might be different from what a creative professional wants for weekend inspiration. The key is to explore — and ask questions.Here’s how to narrow it down:
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